Diagnostic Cytogenetics
Diagnostic Cytogenetics By Friedel Wenzel (auth.), Prof. Dr. Rolf-Dieter Wegner Ph.D. (eds.)
1999 | 460 Pages | ISBN: 3642478131 | PDF | 9 MB
1999 | 460 Pages | ISBN: 3642478131 | PDF | 9 MB
In addition to the traditional cytogenetics still used as the basic methodology for everyday clinical diagnosis, new molecular cytogenetic techniques provide a useful basis for routine diagnosis. Flourescence in situ hybridization (FISH) has become a standard technique, and comparative genomic hybridization (CGH), sprectral karyotyping (SKY), and multi-color FISH have shown their potential for diagnostic purposes. Following a section on tissue culture, chromosome staining and basic information about karyotyping, nomenclature and quality standards, protocols of relevance for comprehensive cytogenetic diagnostics are presented.
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