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"Drug Discovery and Development: Present and Future" ed. by Izet M. Kapetanovic (Repost)

Posted By: exLib
"Drug Discovery and Development: Present and Future" ed. by Izet M. Kapetanovic (Repost)

"Drug Discovery and Development: Present and Future" ed. by Izet M. Kapetanovic
InTeOpP | 2011 | ISBN: 9533076151 9789533076157 | 538 pages | PDF | 20 MB

The authors in the book discuss the current and evolving state of drug discovery and development.

Drug discovery and development process aims to make available medications that are safe and effective in improving the length and quality of life and relieving pain and suffering.
There is a growing urgency to identify and develop more effective, efficient, and expedient ways to bring safe and effective products to the market.
The drug discovery and development process relies on the utilization of relevant and robust tools, methods, models, and validated biomarkers that are predictive of clinical effects in terms of diagnosis, prevention, therapy, and prognosis.
There is a growing emphasis on translational research, a bidirectional bench to the bedside approach, in an effort to improve the process efficiency and the need for further innovations.

Contents
Preface
Introductory: Overview of Current Drug Discovery and Development with an Eye Towards the Future
Part 1 Current Status and Future Directions
1 Drug Discovery and Ayurveda: Win-Win Relationship Between Contemporary and Ancient Sciences
2 Evolutionary Biology and Drug Development
3 Novel Oncology Drug Development Strategies in the Era of Personalised Medicine
4 Drug Discovery into the 21st Century
Part 2 Models
5 Genetically Engineered Mouse Models in Preclinical Anti-Cancer Drug Development
6 Genetic Pharmacotherapy
7 Critical Human Hepatocyte-Based In Vitro Assays for the Evaluation of Adverse Drug Effects
3 The Use of In Vitro 3D Cell Models in Drug Development for Respiratory Diseases
Part 3 Tools, Methods, and Bio markers
9 Chemical Biology: What is Its Role in Drug Discovery?
10 Towards Understanding Drugs on the Molecular Level to Design Drugs of Desired Profiles
11 De-Risking Drug Discovery Programmes Early with ADMET
12 Novel Approach to High Throughput Screening for Activators of Transcription Factors
13 Assessment of Cell Cycle Inhibitors by Flow Cytometry
14 Image-Based High-Content Screening in Drug Discovery
15 Recent Advances in Biotherapeutics Drug Discovery and Development
16 Drug Discovery by Aptamers in Protozoan Infectious Diseases
17 Streamlining ICH Q6B Analytical Testing of Biotherapeutics
18 Bio markers in Drug Development: A Useful Tool but Discrepant Results May Have a Major Impact
Part 4 Drug Delivery
19 Nanotechnology Based Targeted Drug Delivery: Current Status and Future Prospects for Drug Development
20 Silver Nanoparticles - Universal Multifunctional Nanoparticles for Bio Sensing, Imaging for Diagnostics and Targeted Drug Delivery for Therapeutic Applications
21 Mesenchymal Stem Cells as Vehicles for Targeted Therapies
with TOC BookMarkLinks