Cancer Immunotherapy at the Crossroads
Cancer Immunotherapy at the Crossroads: How Tumors Evade Immunity and What Can Be Done by James H. Finke
English | 24 Nov. 2003 | ISBN: 1588291839 | 408 Pages | PDF | 6 MB
English | 24 Nov. 2003 | ISBN: 1588291839 | 408 Pages | PDF | 6 MB
Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction. The authors review the mechanisms of immune dysfunction and evasion mechanisms in histologically diverse human tumors, focusing on tumor-induced molecular defects in T cells and antigen-presenting cells (dendritic cells and tumors), that may serve as biomarkers for patient prognosis