"Reviews on Selected Topics of Telomere Biology" ed. by Bibo Li

This book includes current opinions on selected aspects of telomere research and their implication, to help us focus better on future studies and enhance our research progress.

Telomeres, located at the ends of linear chromosomes, are essential for genome stability and integrity. Advances in telomere researches have linked telomere dysfunction with cellular aging and a number of age-related human diseases.
Recent studies further expanded our knowledge of telomere functions - telomeres are shown to be important for microbial pathogen virulence and telomere proteins have important non-telomeric cellular functions.

Contents
Preface
Section 1 Telomere Length and Its Regulation
1 Telomere Length and Aging
2 Control of Telomere Length in Drosophila
3 The Regulation of Telomerase by Alternative Splicing of TERT
Section 2 Telomeres and Human Diseases
4 Telomere and Telomerase in Cancer: Recent Progress
5 Inhibiting Telomerase Activity and Inducing Apoptosis in Cancer Cells by Several Natural Food Compounds
6 Telomeres and Reproductive Aging
7 Telomeres and Lifestyle Choices
8 Telomere as an Important Player in Regulation of Microbial Pathogen Virulence
Section 3 Noncanonical Functions of the Telomere
9 Extra-Telomeric Roles ofTelomeric Proteins
Section 4 Telomere DNAand Its Evolution
10 Genomic Distribution ofTelomeric DNA Sequences - What Do We Learn from Fish About Telomere Evolution?

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