"Modern Tools for Genetic Engineering" ed. by Michael S.D. Kormann
"Modern Tools for Genetic Engineering" ed. by Michael S.D. Kormann
ITexLi | 2016 | ISBN: 9535123920 9789535123927 | 220 pages | PDF | 10 MB
ITexLi | 2016 | ISBN: 9535123920 9789535123927 | 220 pages | PDF | 10 MB
This book offers insight into the modern tools of genome editing, their hurdles and their huge potential. A new era of in vivo genetic engineering has begun.
Site-specific endonucleases create double-strand breaks within the genome and can be targeted to literally any genetic mutation. Together with a repair template, a correction of the defective locus becomes possible.
Contents
Preface
1 Next-Generation Therapeutics: mRNA as a Novel Therapeutic Option for Single-Gene Disorders
2 Gene Delivery Technologies for Efficient Genome Editing: Applications in Gene Therapy
3 DNA Elements Tetris: A Strategy for Gene Correction
4 Gene Correction Technology and Its Impact on Viral Research and Therapy
5 Gene Editing in Adult Hematopoietic Stem Cells
6 Insulin Gene Therapy for Type 1 Diabetes Mellitus: Unique Challenges Require Innovative Solutions
7 Application of Genome Editing Technology to MicroRNA Research in Mammalians
8 Emerging Gene Correction Strategies for Muscular Dystrophies: Scientific Progress and Regulatory Impact
1st true PDF with TOC BookMarkLinks