"Autophagy: A Double-Edged Sword: Cell Survival or Death?" ed. by Yannick Bailly

The chapters in this book review the latest advances in the molecular mechanisms of autophagy, highlighting some of the most challenging research topics. The focus is mainly on how this basic cell defense mechanism comes into play in various pathologies, including liver diseases, myopathies, infectious diseases, cancers and neurodegenerative diseases.

Contents
Preface
Section 1 New Insights into Mechanisms of Autophagy
1 Role of Human WIPIs in Macroautophagy
2 Atg8 Family Proteins —Autophagy and Beyond
3 Rab GTPases in Autophagy
4 Flow Cytometric Measurement of Cell Organelle Autophagy
Section 2 Consequences of Autophagy Deficits
5 Autophagy, the "Master' Regulator of Cellular Quality Control: What Happens when Autophagy Fails?
6 Altering Autophagy: Mouse Models of Human Disease
Section 3 Autophagy in GNE Myopathy
7 Autophagy in GNE Myopathy
Section 4 Autophagy and the Liver
8 Autophagy and the Liver
Section 5 Autophagy in Cancer
9 Role of Autophagy in Cancer and Tumor Progression
10 Role of Autophagy in Cancer
11 Regulation of Autophagy by Short Chain Fatty Acids in Colon Cancer Cells
12 Natural Compounds and Their Role in Autophagic Cell Signaling Pathways
Section 6 Autophagy in Infectious Diseases
13 Infectious Agents and Autophagy: Sometimes You Win, Sometimes You Lose
14 Autophagic Balance Between Mammals and Protozoa: A Molecular. Biochemical and Morphological Review of Apicomplexa and Trypanosomatidae Infections
15 Induction of Autophagy by Anthrax Lethal Toxin
16 Up-Regulation of Autophagy Defense Mechanisms in Mouse Mesenchymal Stromal Cells in Response to Ionizing Irradiation Followed by Bacterial Challenge
Section 7 Autophagy in Neurodegenerative Diseases
17 Role of Autophagy in Parkinson's Disease
18 Neuronal Autophagy and Prion Proteins
Section 8 Autophagy and Cell Death
19 Role of Autophagy in the Ovary Cell Death in Mammals
20 Autophagy in Development and Remodelling of Mammary Gland
21 Integrin and Adhesion Regulation of Autophagy and Mitophagy
22 Time Flies: Autophagy During Ageing in Drosophila

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