"Autophagy in Current Trends in Cellular Physiology and Pathology" ed. by Nikolai V. Gorbunov and Marion Schneider

This volume is addressed to one of the fundamental molecular mechanisms - autophagy- evolutionarily adopted by cells for processing of unnecessary or malfunctioned constituents and shaping intracellular structures, adjusting them to environmental conditions, aging, disease, neoplasia, and damages over their life period.

Particular attention is paid to autophagy-mediated barrier processes of selective sequestration and recycling of impaired organelles and degradation of invading microorganisms, that is, the processes sustaining intrinsic resistance to stress, tissue degeneration, toxic exposures, and infections. The presented topics encompass personal experience and visions of the chapter contributors and the editors; the book chapters include a broad analysis of literature on biology of autophagy.

Contents
Preface
1 Introductory Chapter: Overview on Autophagy in Burden of Functions
2 Aging-Related Diseases and Autophagy
3 Cell Cycle Analysis of ER Stress and Autophagy
4 High-Mobility Group Box 1 and Autophagy
5 Role of Autophagy in Mediating the Anticancer Effects of Tocotrienols
6 TRAIL Induces Apoptosis and Autophagy
7 The Role of Ubiquitin System in Autophagy
8 HIV‐1, Drug Addiction, and Autophagy
9 Autophagic Flux Failure in Neurodegeneration: Identifying the Defect and Compensating Flux Offset
10 Role of Autophagy in Burn Wound Progression and Wound Healing
11 Autophagy in Model Organisms: Insights into Cancer
12 Autophagy in Plant Pathogenic Fungi
13 Autophagy in Cystic Fibrosis Pathogenesis and Treatment
14 The Role of Autophagy in Lung Disease
15 Autophagy in Ocular Pathophysiology
16 The Role of Autophagy in Maintaining Pregnancy
17 Autophagy Modulation for Organelle-Targeting Therapy
18 Choosing Lunch: The Role of Selective Autophagy Adaptor Proteins
19 Targeting Mitophagy in Combined Therapies of Haematological Malignancies
20 Autophagy in Multidrug-Resistant Cancers
21 Autophagy in Non-Alcoholic Fatty Liver Disease (NAFLD)
22 Autophagy and Coagulation in Liver Cancer and Disorders
23 Role of Autophagy in Cancer Metabolism