"Acute Phase Proteins" ed. by Sabina Janciauskiene

The functional activities of specific APPs and their quantification during the course of acute and chronic inflammation are discussed in this book.

The magnitude and rapidity of the changes in the concentrations of APPs, together with their short half-life, suggest an important role for these proteins in the establishment of host defense. APPs are regarded as having general functions in trapping of micro-organisms and their products, in activating complement, in binding cellular remnants like nuclear fractions, in neutralizing enzymes, scavenging free radicals, and in modulating the hosts immune response. Despite vast pro- and anti-inflammatory properties ascribed to individual APPs, their function during health and disease remains incompletely defined.

Contents
Preface
Chapter 1 Immunoregulatory Properties of Acute Phase Proteins — Specific Focus on a 1-Antitrypsin
Chapter 2 Inflammation and Acute Phase Proteins in Haemostasis
Chapter 3 The Role of Haptoglobin and Its Genetic Polymorphism in Cancer: A Review
Chapter 4 Role of SAAin Promoting Endothelial Activation: Inhibition by High-Density Lipoprotein
Chapter 5 The Use of Acute Phase Proteins as Biomarkers of Diseases in Cattle and Swine
Chapter 6 Molecular Aspects of Human Alpha-1 Acid Glycoprotein — Structure and Function
Chapter 7 Unique Assembly Structure of Human Haptoglobin Phenotypes 1-1, 2-1, and 2-2 and a Predominant Hp 1 Allele Hypothesis

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