Niall Barron, "MicroRNAs as Tools in Biopharmaceutical Production"
2012 | ISBN-10: 9400751273 | 124 pages | PDF | 4,8 MB
2012 | ISBN-10: 9400751273 | 124 pages | PDF | 4,8 MB
Focused manuscript on the potential use/role of miRNAs in bioprocessing, specifically the production of complex proteins in mammalian cells. With that in mind I propose a draft list of topics/chapters along the following lines: Intro on CHO/bioprocessing/engineering challenges to set scene, Genomic organization, biogenesis and mode of action, Identifying miRNA targets: Computational prediction, transcriptomics, proteomices, UTR analysis, etc.