Lysosomes: Biology, Diseases, and Therapeutics
Frederick R. Maxfield, James M. Willard, Shuyan Lu, "Lysosomes: Biology, Diseases, and Therapeutics"
English | ISBN: 1118645154 | 2016 | 562 pages | PDF | 8 MB
English | ISBN: 1118645154 | 2016 | 562 pages | PDF | 8 MB
Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development.
• Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates
• Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair
• Introduces new pathways in therapeutic development and new mechanisms in drug development